产品货号：
Z11838
中文名称：
BAG3抗体
英文名称：
Anti-BAG3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BAG3 Antibody |
| 指标别名 | BAG 3;BAG3;BIS;CAIR 1;Docking protein CAIR 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | BAG3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Bag3(491-506aa LEKLEQKAIDVPGQVQ),identical to the related mouse and rat sequences. |
| 实际分子量 | 80KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | BAG family molecular chaperone regulator 3(BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones.BAG3 mutations are responsible for familial dilated cardiomyopathy.BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus.In muscle cells,BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes.This process is called chaperone-assisted selective autophagy(CASA) and is essential for maintaining muscle activity in flies,mice and men. |
| Uniprot ID | O95817 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | BCL2-associated athanogene 3 |
| 蛋白名全称 | BAG family molecular chaperone regulator 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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